spd l2 (Galectin Therapeutics)
86
Structured Review
Galectin Therapeutics
spd l2
Spd L2, supplied by Galectin Therapeutics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/spd-l2/pmc12902033-104-31-32?v=Galectin+Therapeutics
Average 86 stars, based on 1 article reviews
Spd L2, supplied by Galectin Therapeutics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/spd-l2/pmc12902033-104-31-32?v=Galectin+Therapeutics
Average 86 stars, based on 1 article reviews
spd l2 - by Bioz Stars,
2026-08
86/100 stars
Images
1) Product Images from "Identification of a circulating immunological signature as a liquid biopsy approach for the diagnosis of endometriosis"
Article Title: Identification of a circulating immunological signature as a liquid biopsy approach for the diagnosis of endometriosis
Journal: Scientific Reports
doi: 10.1038/s41598-026-36464-8
Figure Legend Snippet: Circulating levels of cytokines and soluble immune checkpoints in patients suffering from endometriosis. The concentration of cytokines ( A ) IL-4, IL-2, IL-1β, IL-6, IL-10, IFN-γ, IL-12p70, IL-17A, TNF, TGF-β1, IP-10(CXCL10), MCP-1(CCL2) and IL-8 and soluble immune checkpoints ( B ) sSiglec-5, sB7.2(CD86), sCD25, sPD-L2, Galectin-9, sPD-L1, sTim-3, sCTLA-4, sPD-1, s4-1BB, sCD27, and sLAG3 was analyzed in blood soluble fractions of controls (women scheduled for salpingectomy with contraception purposes) and patients diagnosed with endometriosis. Data are shown as box and whiskers showing quartiles. Comparisons between the two groups of participants were performed by Mann–Whitney test. P values are represented as * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.
Techniques Used: Concentration Assay, MANN-WHITNEY
Figure Legend Snippet: Regression model considering circulating immunological factors identify patients suffering from endometriosis. Wald backward stepwise regression, including as variables those statistically different in Fig. (TNF, TGF-β1, IP-10, MCP-1, IL-8, sCD25, sPD-L2, Galectin-9, sPD-L1, sTim-3, sCTLA-4, sPD-1, s4-1BB, sCD27 and sLAG-3) was performed. ( A ) Optimal model differentiating patients suffering from endometriosis from controls (women scheduled for salpingectomy with contraception purposes). ( B ) ROC curve analysis for identification of endometriosis. C Distribution of controls and patients diagnosed with endometriosis according to the score generated as the optimal Youden index from the ROC curve in B. Area under the curve (AUC) is shown, as well as sensitivity and specificity of 95% confidence intervals are shown in brackets. **** p < 0.0001, Mann–Whitney test.
Techniques Used: Generated, MANN-WHITNEY
Figure Legend Snippet: Regression model including age and BMI generates a minimal signature of clinical application for the diagnosis of endometriosis. Wald backward stepwise regression, including as variables those immunological factors statistically different in Fig. (TGF-β1, TNF, IP-10, MCP-1, IL-8, sCD25, sPD-L2, Galectin-9, sPD-L1, sPD-1, sCTLA-4, sTim-3, s4-1BB, sCD27 and sLAG-3) plus age and body mass index (BMI) of the participants was performed. ( A ) Optimal model differentiating patients suffering from endometriosis from controls (women scheduled for salpingectomy with contraception purposes). ( B ) ROC curve analysis for identification of endometriosis. ( C ) Distribution of controls and patients diagnosed with endometriosis according to the score generated as the optimal Youden index from the ROC curve in B. Area under the curve (AUC) is shown, as well as sensitivity and specificity of 95% confidence intervals are shown in brackets. **** p < 0.0001, Mann–Whitney test.
Techniques Used: Biomarker Discovery, Generated, MANN-WHITNEY
